The smart Trick of ceesdekker.net That Nobody is Discussing
The smart Trick of ceesdekker.net That Nobody is Discussing
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Rotary motion of DNA rotors on nanopores. Major row: raw video with the Cy5 channel of each rotor. Center row: corresponding solitary-particle localization results of both equally ends with the DNA rotors. The placement of the present frame is marked as orange and blue dots, and the trajectory of the 10 frames before The present body is proven as good traces.
Reconstitution of ultrawide DNA origami pores in liposomes for transmembrane transport of macromolecules
‘It was simply just a make any difference of finding up a ebook on cell biology and beginning to examine. I had originate from a earth of ultra-higher vacuums, cryostats and quantum phenomena, and now I had been Doing work at space temperature with molecular biology kits.
Sculpting nano-electrodes using a transmission electron beam for electrical and geometrical characterization of nanoparticles.
2015, discovery that condensin is actually a highly adaptable protein construction; and initial detection of DNA knots using nanopores
Cornelis (Cees) Dekker (Haren, seven april 1959) is een Nederlandse natuurkundige en universiteitshoogleraar verbonden aan de Technische Universiteit Delft. Van 2010 tot en fulfilled 2018 was hij tevens directeur van het Kavli Institute of Nanoscience in Delft. Zijn vakgebied is de moleculaire biofysica; hierbij beweegt hij zich op het grensvlak van de natuurkunde en de biologie waarbij hij gebruikmaakt van de zogeheten nanotechnologie, de technieken om aan enkele atomen en moleculen te kunnen meten.
We use nanofabricated microfluidic constructions to pattern spatial boundaries for germs and biomimetic vesicles with reconstituted protein networks and this evaluate the elemental job of spatial confinement within the molecular and mobile stage. Our initiatives incorporate the next:
Dynamic ParB–DNA interactions initiate and keep a partition condensate for bacterial chromosome segregation
In 1993, like a younger and keen affiliate professor at Delft University of Technological innovation, I'd initially targeted the exploration endeavours of my group on measuring the electrical conductance of just one conducting-polymer molecule. Within just two years, we had developed a tool wherein a single wire of a phthalocyaninepolysiloxane polymer was linked amongst two intently spaced metallic nanoelectrodes.
But carbon nanotubes have remained a study topic of considerable interest to lots of. Indeed, the outlook on using carbon nanotubes to build simple equipment, in parts for instance radio-frequency electronics, digital electronics and flexible electronics, continues to be dazzling.
FtsZ treadmilling is important for Z-ring condensation and septal constriction initiation in bacterial mobile division
2006, first demonstration of molecular sorting in the lab with a chip utilizing biomotors; discovery of nanobubbles in good-state nanopores; and very first estimate of electrokinetic Electricity conversion inside a nanofluidic channel
Developments in nanotechnology inside the nineties manufactured making Digital devices from single molecules a chance. Cees Dekker recounts how his crew made a room-temperature transistor according to just one carbon nanotube.
2004, discovery of new physics in translocation of DNA as a result of nanopores; initially experimental examine of ions conduction in nanofluidic channels; initial ceesdekker electrochemistry with individual solitary-wall carbon nanotubes; STM detection and control of phonons in carbon nanotubes; to start with electrical docking of microtubules on kinesin-coated nanostructures; 1st biophysics characterization in the mechanical Attributes of double-stranded RNA; and initially single-molecule analyze of DNA translocation by a restriction-modification enzyme.